Traumatic Brain Injury (TBI): Can Low-Dose Naltrexone (LDN) Provide Support?
- Kevin Keane
- Sep 30, 2024
- 2 min read
What is Traumatic Brain Injury?
Traumatic brain injury (TBI) is a significant public health issue, affecting millions of individuals in the U.S. annually. Around 1.7 million TBIs occur in the U.S. each year, leaving between 2.5 and 6.5 million Americans living with disabilities as a result.
TBI occurs when a powerful blow or jolt to the head disrupts normal brain function. This can happen when the head violently strikes an object or when an object penetrates the skull, damaging brain tissue. While mild TBIs may temporarily affect mental status, more severe cases can lead to extended periods of unconsciousness or even death. Survivors of TBI often experience long-term challenges, including difficulties with thinking, memory, movement, sensation, or emotional regulation. Common causes include falls, vehicle accidents, sports or combat injuries, violence, and explosions.
Because TBI is a medical emergency, prompt treatment is critical for improving chances of recovery. Emerging research suggests that low-dose naltrexone (LDN) may assist in the recovery process for TBI patients.
What is Low-Dose Naltrexone (LDN)?
Initially approved by the FDA in 1984 to treat opioid addiction, naltrexone later showed promise in low doses—about one-tenth of its standard dose—for its anti-inflammatory and immune-modulating properties. LDN has gained attention for its potential to manage various conditions with minimal side effects, no risk of abuse, and a relatively low cost due to the small dosage required. Studies have indicated positive outcomes with LDN in a variety of conditions, and it has now been considered in the context of TBI recovery.
How Can Low-Dose Naltrexone (LDN) Help TBI Patients?
The immune-regulating and anti-inflammatory effects of LDN may aid the body's response to the damage caused by TBI, such as infection and inflammation, while also reducing brain swelling to limit further harm. Additionally, LDN has been shown to help manage pain related to brain injury and may promote faster recovery in TBI patients.
Further Resources
If you are interested in learning more about LDN and its potential benefits for traumatic brain injury, consider visiting the LDN Research Trust website. There, you can read patient stories and explore the latest research. It’s also recommended to consult with your healthcare provider to discuss whether LDN might be a suitable option for you.
Written by:
Joseph Gagnon Jr.